Oriva

A Non-invasive Solution for Diagnosing Neonatal Sepsis

OVi is a reimagined airplane seat that introduces a leaning posture to improve passenger comfort on long-haul economy flights — without requiring any changes to cabin layout or seat pitch. Rather than keeping passengers in a rigid seated position for hours, OVi allows users to switch between sitting and standing-leaning, relieving spinal pressure and improving circulation. It folds up when not in use, opening space in the aisle and making entry and exit easier.

OVi is a reimagined airplane seat that introduces a leaning posture to improve passenger comfort on long-haul economy flights — without requiring any changes to cabin layout or seat pitch.

Role:

Product Design Engineer

Duration:

4 Months

Type:

Team Project

Sepsis

is a life-threatening whole-body response to infection in which the immune system attacks the body itself, silently destroying organs and tissues

Even For Babies
Who Survive Sepsis

the impacts often carry throughout their entire lifespan.

“Blood culture is the standard practice, but it takes time.”
"Blood Culture is the standard practice, but it takes time.”
“Blood culture is the standard practice, but it takes time.”

-Dr. Maron Jill

Chief of Pediatrics, Department of Pediatrics at Women & Infants Hospital

10ML of Blood

Too much for Infant

Up to 5 Days of Time

Too long for Sepsis

10ML of Blood

Too much for Infant

Up to 5 Days of Time

Too long for Sepsis

What if we can shorten the process
from 5 days to 2 hours ?
What if we can shorten the process
from 5 days to 2 hours ?
What if we can shorten the process
from 5 days to 2 hours ?

Faster Accurate Treatment + Less Antibiotics Overdose

By using Saliva as the Non-invasive
Triage Alternative
By using Saliva as the Non-invasive
Triage Alternative

In Collaboration with with Team NeoSense at Harvard Medical School

Demo Video
Demo Video
Three Step Design
Collect
Test
Diagnosis
Saliva Collection - Current Solution
Not Standardized

Not Standardized

Not Standardized

Improvised DIY Steps

Improvised DIY Steps

Needs Wall-Suction

Needs Wall-Suction

Needs Wall-Suction

Infrastructure Demanding

Infrastructure Demanding

Non-Intuitive

Non-Intuitive

Non-Intuitive

Uneven Grip

Uneven Grip

Exploration

We found the existing approach promising and built on it by developing an easy-to-use, portable handheld device that can both collect saliva and eject it for the next step. Here are some of the internal mechanisms we explored.i

We found the existing approach promising and built on it by developing an easy-to-use, portable handheld device that can both collect saliva and eject it for the next step. Here are some of the internal mechanisms we explored.i

Manual Pump with single valve

Electrical Pump with Large Syringe Covering Inlet and Outlet

Electrical Pump with Manual Ejection

Electrical Pump with 2 Solenoid Valves

Electrical Pump with 2 Solenoid Valves

Electrical Pump with 2 Solenoid Valves

Final Collection Device
Final Collection Device

Squeeze to Extract

Squeeze to Extract

Squeeze to Extract

Push to Eject

Push to Eject

Push to Eject

Exploded View
Exploded View
ELISA Testing - Current Solution
Hard to Transport

Hard to Transport

Hard to Transport

Size of a Fridge

Complex Operation

Complex Operation

Complex Operation

Requires Expertise

Requires Cold Chain

Requires Cold Chain

Requires Cold Chain

Temperature for Sample: -80 degree

Intervention
10 Times Smaller

Portable

All in One

Reduce Steps

Current Technology
Intervention
10 Times Smaller
10 Times Smaller

Portable

All-in-One
All-in-One

Reduce Steps

Microfluidics Disc Design
Microfluidics Disc Design
Microfluidics Disc Design

Saliva input in the center

Saliva input in the center

Disc spins at 250 RPM

Disc spins at 250 RPM

Saliva gets to reaction chamber

Saliva gets to reaction chamber

Disc oscillates and then spins at 650 RPM

Disc oscillates and then spins at 650 RPM

Saliva gets to waste chamber

Saliva gets to waste chamber

Form Exploration on CAD
Form Exploration on CAD
Rapid Prototyping
Rapid Prototyping
Selected Projects

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